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Pregabalin 75 mg – Effective Treatment for Nerve Pain, Seizures & Anxiety

🔹 What is Pregabalin 75 mg?

Pregabalin 75 mg is a prescription medication used to treat nerve pain, seizures, and anxiety disorders. It belongs to the class of drugs known as anticonvulsants or alpha-2-delta ligands. Although structurally related to gamma-aminobutyric acid (GABA), it doesn’t act directly on GABA receptors. Instead, it reduces the release of pain signals by binding to calcium channels in the nervous system.

🔹 Key Uses of Pregabalin 75 mg

Medical Condition	Effect of Pregabalin
Neuropathic pain (diabetes, shingles, SCI)	Relieves nerve-related pain and tingling
Fibromyalgia	Reduces widespread pain and fatigue
Partial-onset seizures	Adjunctive therapy for epilepsy
Generalized Anxiety Disorder (GAD)	Helps control excessive anxiety and restlessness

🔹 How It Works

Pregabalin binds to the α2-δ subunit of voltage-gated calcium channels in the central nervous system. This inhibits the release of excitatory neurotransmitters (like glutamate, substance P, and noradrenaline), leading to reduced nerve signal transmission and pain sensation.

🔹 Dosage and Administration

• Typical starting dose: 75 mg twice daily
• Maximum dose: Up to 600 mg/day (in divided doses), depending on condition
• Route: Oral – can be taken with or without food

⚠️ Always follow the prescribed dose from your healthcare provider. Do not self-adjust.

🔹 Common Side Effects

Mild to Moderate Side Effects	Severe (Rare)
Dizziness, sleepiness, fatigue	Suicidal thoughts or behavior
Dry mouth	Swelling in limbs
Blurred vision	Allergic reaction (rash, itching)
Weight gain	Difficulty breathing
Trouble concentrating	Muscle pain or weakness

🔹Precautions & Warnings

• ⚠️ Not for use in pregnancy unless clearly needed
• 🚫 Avoid alcohol (increased drowsiness and dizziness)
• 💊 Gradual tapering required to discontinue – sudden stoppage can cause withdrawal
• 🚘 May impair ability to drive or operate machinery
• 🩺 Use with caution in patients with kidney disease

🔹Drug Interactions

• Increases effects of CNS depressants (alcohol, opioids, benzodiazepines)
• May interact with certain antidepressants or antihypertensives
• Always inform your doctor about all medications and supplements you’re taking.

🔹Storage Instructions

• Store at room temperature (20–25°C)
• Keep away from moisture and heat
• Keep out of reach of children
• Do not use expired medication