β Ciplox 250 mg β Trusted Antibiotic for UTIs, Respiratory & GI Infections
π What is Ciplox 250 mg?
Ciplox 250 mg is an oral antibiotic containing Ciprofloxacin, a broad-spectrum fluoroquinolone used to treat a wide range of bacterial infections. It is particularly effective against gram-negative bacteria and is often prescribed for urinary tract infections (UTIs), respiratory infections, skin infections, and gastrointestinal infections.
βοΈ Mechanism of Action
Ciprofloxacin works by inhibiting DNA gyrase and topoisomerase IV, essential enzymes bacteria need to replicate and repair their DNA. This causes bacterial cell death, making it bactericidal in nature.
β Indications / Uses
Ciplox 250 mg is used to treat infections caused by susceptible bacteria, including:
- Urinary Tract Infections (UTIs)
- Lower Respiratory Tract Infections (e.g., bronchitis, pneumonia)
- Gastrointestinal infections (e.g., travelerβs diarrhea, typhoid fever)
- Sinusitis
- Skin and soft tissue infections
- Prostatitis (bacterial)
- Bone and joint infections
- Certain sexually transmitted infections (e.g., gonorrhea)
π Dosage and Administration
Dosage depends on the type and severity of infection. Follow your doctorβs instructions.
Typical Adult Dosing:
Condition | Usual Dose (Adults) |
UTIs (mild/moderate) | 250 mg twice daily for 3β7 days |
Gastrointestinal infections | 250β500 mg twice daily for 3β7 days |
Respiratory infections | 500β750 mg twice daily |
Administration Tips:
- Swallow the tablet whole with water
- Take before or after meals, but avoid dairy/calcium-rich food around dosing
- Drink plenty of fluids
- Take at even intervals (e.g., every 12 hours)
β οΈ Warnings & Precautions
- Avoid in children and adolescents unless absolutely necessary
- Tendon rupture risk β especially in elderly or corticosteroid users
- Can cause CNS effects (dizziness, seizures, confusion)
- Not recommended in pregnancy or breastfeeding
- Use cautiously in patients with kidney impairment β dosage adjustment may be needed
π’ Side Effects
Common:
- Nausea
- Diarrhea
- Headache
- Dizziness
- Abdominal discomfort
Rare but Serious:
- Tendonitis or tendon rupture
- Allergic reactions (rash, swelling, anaphylaxis)
- QT interval prolongation
- Liver enzyme abnormalities
- Photosensitivity (sensitivity to sunlight)
π Drug Interactions
Ciprofloxacin can interact with:
- Antacids, iron, calcium, and multivitamins β reduce drug absorption
- Warfarin β may enhance anticoagulant effect
- Theophylline β increases toxicity risk
- NSAIDs β risk of seizures when used together
- Clozapine, tizanidine, or cyclosporine β potential for serious reactions
π Important: Separate Ciplox and antacid/dairy intake by at least 2β4 hours.
π€° Use in Pregnancy and Lactation
- Pregnancy: Generally not recommended unless benefits outweigh risks
- Breastfeeding: Use with caution; small amounts can pass into breast milk
π¦ Storage Information
- Store below 25Β°C (77Β°F)
- Protect from moisture and light
- Keep out of reach of children
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