✅ Doxycycline 100 mg – Trusted Antibiotic for Bacterial Infections, Acne & Malaria Prevention

🔍 What is Doxycycline 100 mg?

Doxycycline 100 mg is a broad-spectrum antibiotic used to treat a variety of bacterial infections. It belongs to the tetracycline class and works by inhibiting bacterial protein synthesis, effectively halting the growth of harmful bacteria.

Doxycycline is also widely used for malaria prevention, acne treatment, and certain inflammatory conditions like rosacea.

⚙️ How It Works (Mechanism of Action)

Doxycycline binds to the 30S ribosomal subunit of bacteria, preventing the attachment of aminoacyl-tRNA to the ribosome. This disrupts protein production and halts bacterial replication.

✅ Common Indications (Uses)

Doxycycline 100 mg is used for:

• Respiratory tract infections (pneumonia, bronchitis)
• Urinary tract infections (UTIs)
• Sexually transmitted infections (chlamydia, gonorrhea, syphilis)
• Acne and rosacea
• Skin infections
• Eye infections (e.g., trachoma)
• Rickettsial infections (Rocky Mountain spotted fever, typhus)
• Malaria prophylaxis
• Anthrax (including post-exposure)
• Periodontal (gum) disease

💊 Dosage and Administration

Always follow your doctor’s prescription.

Typical Dosage:

• Adults: 100 mg twice daily or 200 mg once daily
• Malaria prevention: 100 mg daily starting 1–2 days before travel and continued for 4 weeks after leaving the area
• Take with a full glass of water, and remain upright for 30 minutes afterward
• Avoid taking with dairy, calcium, or antacids, which may reduce absorption

⚠️ Precautions and Warnings

• Not recommended for children under 8 years (may cause permanent teeth discoloration)
• Avoid during pregnancy unless essential (can affect fetal bone growth)
• Use caution in patients with liver problems
• Can cause photosensitivity – use sunscreen and avoid excessive sunlight
• Take with food to reduce stomach upset (but avoid calcium-rich foods at the same time)

💢 Common Side Effects

Common	Rare/Serious
Nausea and vomiting	Severe allergic reactions
Diarrhea	Intracranial hypertension (headache, blurred vision)
Abdominal pain	Esophageal irritation or ulcers
Skin rash	Liver toxicity

🔄 Drug Interactions

Avoid combining Doxycycline with:

• Antacids containing aluminum, magnesium, or calcium
• Iron or zinc supplements (take 2 hours apart)
• Oral contraceptives (may reduce effectiveness)
• Blood thinners (like warfarin – dosage may need adjustment)
• Penicillin antibiotics (reduced effectiveness)

🤰 Use in Pregnancy and Breastfeeding

• Pregnancy: Not recommended during 2nd and 3rd trimester
• Breastfeeding: Passes into breast milk – avoid prolonged use

📦 Storage Instructions

• Store at room temperature (15–30°C)
• Keep away from light, moisture, and heat
• Do not use expired Doxycycline – it can be toxic if degraded