💊 Fliban – Complete Guide to Uses, Benefits, and Dosage

✅ 1. What is Fliban?

Fliban is a medication used to treat hypoactive sexual desire disorder (HSDD) in women, specifically premenopausal women. It is often marketed under the brand name Addyi. Fliban acts as a neuromodulator by influencing certain neurotransmitters in the brain, improving sexual desire and overall satisfaction. It works by addressing the imbalance of serotonin, dopamine, and norepinephrine, which play significant roles in sexual function.

✅ 2. How Does Fliban Work?

it works primarily by modulating neurotransmitters in the brain. It increases dopamine and norepinephrine levels while reducing serotonin activity in certain brain regions. This alteration is believed to boost sexual desire in women with HSDD.

• Increased dopamine helps stimulate sexual desire.
• Reduced serotonin levels prevent inhibition of sexual activity.

🔬 it does not directly cause sexual arousal but enhances the desire for it when paired with a stimulating environment.

✅ 3. Indications (Uses)

Fliban is approved for the treatment of hypoactive sexual desire disorder (HSDD) in premenopausal women. HSDD is characterized by a lack of sexual desire that causes significant distress and is not related to any underlying medical condition or medication side effects.

Primary Indication:

• Hypoactive Sexual Desire Disorder (HSDD) in premenopausal women: Fliban is used to increase sexual desire and alleviate distress caused by low libido.

✅ 4. Dosage and Administration

The recommended dosage of Fliban is 100 mg taken once daily at bedtime. This is because the medication can cause drowsiness and taking it at night reduces the risk of daytime side effects.

• Usual Dose: 100 mg daily (taken at bedtime)
• Missed Dose: If you miss a dose, take it as soon as you remember, unless it’s almost time for your next dose. Do not double the dose to make up for a missed dose.

⚠️ It is important to follow the prescribed dosage and not to adjust the dose on your own.

✅ 5. Benefits of Fliban

• Improves sexual desire in women with HSDD
• Reduces stress and anxiety related to low libido
• Non-hormonal treatment option for sexual dysfunction
• Can improve relationship satisfaction due to increased intimacy
• Not associated with addiction or physical dependence

✅ 6. Side Effects

🔹 Common Side Effects:

• Dizziness
• Fatigue
• Nausea
• Sleepiness

🔹 Serious Side Effects (seek medical attention):

• Severe hypotension (low blood pressure)
• Syncope (fainting)
• Unusual changes in mood, such as depression or anxiety

⚠️ Fliban should not be taken with alcohol as it can increase the risk of severe side effects, including dangerously low blood pressure.

✅ 7. Warnings & Precautions

• Alcohol Interaction: Alcohol can significantly increase the risk of serious side effects like low blood pressure and fainting. Fliban should not be taken with alcohol.
• Liver Impairment: Use cautiously in individuals with liver disease as it can lead to increased blood levels of the drug.
• Hypotension: People with low blood pressure or on medications for hypertension should use Fliban with caution.
• Mental Health: Use caution if you have a history of depression or other mental health conditions. Monitor for worsening of mood or suicidal thoughts.

✅ 8. Contraindications

Fliban is contraindicated in the following conditions:

• Alcohol consumption (due to increased risk of severe low blood pressure and fainting)
• Liver disease (severe hepatic impairment)
• Pregnancy and breastfeeding (Fliban has not been studied in pregnant or breastfeeding women and is not recommended in these populations)

✅ 9. Drug Interactions

Fliban may interact with various medications, especially those affecting liver enzymes or blood pressure. Some of the common interactions include:

• CYP3A4 inhibitors (e.g., ketoconazole, itraconazole) – can increase Fliban levels.
• CYP3A4 inducers (e.g., rifampin, carbamazepine) – may decrease the effectiveness of Fliban.
• Drugs for blood pressure – Fliban can increase the risk of hypotension when combined with medications like nitrates or antihypertensive drugs.

⚠️ Always inform your healthcare provider about all medications you are taking, including over-the-counter drugs.

✅ 10. Storage Instructions

• Store Fliban at room temperature, between 20°C to 25°C (68°F to 77°F).
• Protect from light and moisture.
• Keep out of reach of children.