✅ Pirfenex 200 mg – Trusted Treatment for Idiopathic Pulmonary Fibrosis

🔍 What is Pirfenex 200 mg?

Pirfenex 200 mg contains Pirfenidone, a medication primarily used for the treatment of Idiopathic Pulmonary Fibrosis (IPF)—a chronic and progressive lung disease where lung tissue becomes scarred and thickened, making breathing difficult.

Pirfenidone works by slowing the progression of fibrosis (scarring) and inflammation in lung tissues, helping preserve lung function and improve quality of life over time.

✅ Uses of Pirfenex 200 mg

Pirfenex 200 mg is used to:

• Treat Idiopathic Pulmonary Fibrosis (IPF)
• Slow progression of lung fibrosis
• Improve exercise tolerance and respiratory health

It is sometimes studied for use in other fibrotic conditions but is officially approved for IPF.

💊 Dosage and Administration

Pirfenex 200 mg is often used as part of a gradual dose escalation schedule, to reduce the risk of side effects:

Typical Titration Schedule:

• Week 1: 200 mg tablet 3 times a day (600 mg/day)
• Week 2: 400 mg 3 times a day (1200 mg/day)
• Week 3 onward (maintenance): 600 mg 3 times a day (1800 mg/day)

This may mean taking multiple Pirfenex 200 mg tablets per dose.

Instructions:

• Take with food to reduce nausea
• Swallow tablets whole with water
• Take at evenly spaced intervals (every ~8 hours)

⚙️ How Pirfenex 200 mg Works

Pirfenidone has antifibrotic, anti-inflammatory, and antioxidant properties. It works by modulating the activity of pro-fibrotic cytokines such as TGF-β (Transforming Growth Factor Beta), helping to reduce fibroblast proliferation and collagen formation—key contributors to fibrosis.

⚠️ Precautions and Warnings

• Liver Function Monitoring is essential; regular blood tests may be required
• Avoid sun exposure and use sunscreen due to risk of photosensitivity
• Do not consume alcohol excessively as it may increase liver toxicity
• Use with caution in people with kidney or liver impairment
• Not for use in children or during pregnancy/breastfeeding unless advised by a specialist

💢 Possible Side Effects of Pirfenex 200 mg

Report any signs of jaundice, dark urine, persistent nausea, or rashes to your healthcare provider immediately.

🔄 Drug Interactions

Avoid combining Pirfenex with:

• Ciprofloxacin or fluvoxamine (increases pirfenidone levels)
• Smoking (reduces drug effectiveness)
• Strong CYP1A2 inhibitors without dose adjustment

Always inform your doctor about all medications, including herbal supplements.

📦 Storage Instructions

• Store at room temperature (15°C to 30°C)
• Keep away from direct light and moisture
• Keep out of reach of children