✅ Seroflo Ciphaler 500 mcg: Inhaler for Asthma & COPD – Uses, Dosage & Side Effects

What is Seroflo Ciphaler?

Seroflo Ciphaler is a combination inhaler containing fluticasone propionate (a corticosteroid) and salmeterol xinafoate (a long-acting beta-agonist). It’s primarily used in the treatment of asthma and chronic obstructive pulmonary disease (COPD) to control symptoms, reduce inflammation, and improve lung function.

✅ Indications (Uses)

Seroflo Ciphaler 500 is used for the maintenance treatment and prevention of symptoms in:

🔹 Asthma (Moderate to Severe Persistent)

• Helps prevent wheezing, shortness of breath, and asthma attacks

🔹 Chronic Obstructive Pulmonary Disease (COPD)

• Reduces the frequency and severity of exacerbations
• Improves lung function and quality of life

Not for acute relief of asthma symptoms or during a sudden asthma attack.

⚙️ Mechanism of Action

🔸 Fluticasone Propionate (500 mcg)

• A potent inhaled corticosteroid
• Reduces airway inflammation, swelling, and mucus production
• Helps control long-term asthma symptoms

🔸 Salmeterol (50 mcg)

• A long-acting bronchodilator (LABA)
• Relaxes bronchial smooth muscles to open airways
• Provides up to 12 hours of bronchodilation

Together, they control both the underlying inflammation and bronchoconstriction, making this combination ideal for chronic respiratory conditions.

🕒 Dosage & Administration

📌 Recommended Adult Dose:

• One inhalation twice daily (morning and evening)
• Inhale through the mouth using the Ciphaler device

📌 Administration Tips:

• Use exactly as prescribed
• Rinse mouth after each use to reduce the risk of oral thrush
• Do not exceed recommended dose
• Do not use to treat sudden breathing problems

It may take a few days to weeks for full benefits to be seen.

⚠️ Side Effects

Common Side Effects:

• Headache
• Hoarseness or throat irritation
• Cough
• Oral thrush (fungal infection in the mouth)
• Nausea or upset stomach

Serious (Rare) Side Effects:

• Paradoxical bronchospasm (worsening breathing)
• Increased heart rate or palpitations
• Vision problems (e.g., blurred vision, glaucoma)
• Adrenal suppression (with long-term use)
• Allergic reactions (rash, swelling, difficulty breathing)

Report any unusual or severe side effects to a doctor immediately.

🛑 Warnings & Precautions

• Not for emergency use (does not replace a rescue inhaler like salbutamol)
• Use cautiously in people with:
  • Heart disease
  • Hypertension
  • Thyroid disorders
  • Diabetes
• Risk of oral candidiasis – rinse mouth after use
• Not recommended in children under 12 years without medical advice
• Long-term use may affect bone density, growth (in children), or eye health

🔄 Drug Interactions

May interact with:

• Beta-blockers (may reduce effectiveness)
• Strong CYP3A4 inhibitors (e.g., ketoconazole, ritonavir) – may increase fluticasone levels
• Diuretics – increased risk of hypokalemia
• Other corticosteroids – may increase systemic side effects

📦 Storage Instructions

• Store in a cool, dry place, below 30°C (86°F)
• Keep away from moisture and heat
• Do not wash or submerge the Ciphaler
• Keep out of reach of children