Flohale 2 mg Respules: Complete Guide to Uses, Dosage, Side Effects & Nebulizer Instructions

What is Flohale Respules?

Flohale Respules contain the active ingredient fluticasone propionate, a corticosteroid used in the treatment of asthma and chronic obstructive pulmonary disease (COPD). It works by reducing inflammation in the airways, helping to improve breathing and control symptoms such as wheezing, coughing, and shortness of breath when administered via a nebulizer.

1. Composition

Each respule contains:

• Fluticasone Propionate 2 mg in 2 mL of sterile isotonic saline solution

Other ingredients may include sodium chloride and water for injection.

2. Indications (Uses)

Flohale 2 mg Respules are used primarily in the treatment and management of:

• Bronchial asthma (maintenance therapy)
• Chronic Obstructive Pulmonary Disease (COPD)
• Allergic airway inflammation
• Refractory wheezing in children (especially with underlying inflammation)

Key benefits:

• Reduces frequency and severity of asthma attacks
• Helps improve airflow and breathing
• Controls chronic airway inflammation

It is not intended for emergency use (i.e., not a rescue medication).

3. Mechanism of Action

Fluticasone is a potent inhaled corticosteroid (ICS) that works by:

• Suppressing inflammation in the airways
• Reducing swelling, mucus production, and hyperresponsiveness
• Improving long-term respiratory function

Its local effect in the lungs minimizes systemic steroid side effects when used as directed.

4. Dosage and Administration

Typical Dosage:

• Adults and adolescents (12+ years): 2 mg once or twice daily, as prescribed
• Children (4–11 years): Usually a lower strength is prescribed, but under medical supervision, 2 mg may be used in severe cases

Always follow the dose prescribed by a healthcare provider.

How to Use Flohale Respules:

1. Shake the respule gently.
2. Open the respule and pour the contents into the nebulizer chamber.
3. Connect the nebulizer to a compressor and inhale the mist via a mask or mouthpiece.
4. Inhale the full dose over 10–15 minutes.
5. Rinse the mouth with water after use to prevent oral fungal infections.

5. Side Effects

Common:

• Hoarseness or voice changes
• Throat irritation
• Oral thrush (fungal infection in the mouth)
• Cough after inhalation

Less Common:

• Headache
• Nausea
• Dry mouth or throat

Rare/Serious:

• Suppression of adrenal function (with long-term high doses)
• Growth retardation in children (rare and dose-dependent)
• Allergic reactions (rash, swelling, difficulty breathing)

6. Warnings and Precautions

• Not for sudden asthma attacks – use a rescue inhaler like salbutamol instead.
• Avoid abrupt discontinuation – especially with long-term use.
• Children: Monitor growth during long-term therapy.
• Oral hygiene: Rinse mouth after each dose to prevent fungal infections.
• Use caution in:
  • People with active or untreated infections (e.g., TB)
  • Recent nasal or respiratory surgery

7. Drug Interactions

May interact with:

• Ritonavir or ketoconazole – increases systemic steroid levels
• Other corticosteroids – risk of additive effects
• Immunosuppressive agents – additive immunosuppression

8. Storage Instructions

• Store below 25°C (do not freeze).
• Protect from light and moisture.
• Use immediately after opening a respule.
• Keep out of reach of children.